MendelStar!
Mendel's
rules are the based on simplifying assumptions--the genes being considered
are in unrelated places in the genome, that they live on 'generic' nuclear
chromosomes, and that gene products under study have no interaction
with each other. What happens when one or more of these assumptions
are invalid? Using a hypothetical organism (hey--the truth is out there,
but it isn't very tractable!) you'll learn how to recognize and distinguish
between these sorts of misbehaviors.
Click the above link to proceed to the simulation.
Overview
of this assignment (includes example NOTEBOOK write up)
Meredith Henderson, a previous MCB422 TA, wrote
a primer
on the chi-square test;
I modified it slightly and posted it.
Required
reading:
Mendel's 1865 paper on pea genetics. It's thoughtful, clearly written,
and better science than 95% of the junk in circulation today.
Start at Electronic
Scholarly Publishing
Click on the AUTHOR (with notes) link on the left, then find Mendel. You're
looking for 'Experiments in Plant Hybridization'; I found the English
version more approachable than the original, but then I don't know German...
NDSU
site with some stuff that you may
find useful

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